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OPA-based assays are more sensitive but unstable, which affects accuracy and precision [86], whereas DTNB-based assays allow for determination of biothiols in the presence of other amino acids and polyphenolic antioxidants but are less sensitive [82]

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As a result, the blood levels of injectable TB-500 is usually close to 100%, meaning the entire dose reaches the systemic circulation and is available for action

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