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Finally, we demonstrate that a newly developed DDX3X PROTAC degrader J10 efficiently delays lung cancer progression with multiple advantages compared to DDX3X small molecular inhibitor RK-33 and limited side effects

Tumor Microenvironment Shapes Colorectal Cancer Progression, Metastasis, and Treatment Responses

The cell suspension was washed and centrifuged twice at 1,000 rpm at 4C and resuspended in DMEM enriched with 2 mM glutamine, 50 g/l gentamicin sulfate, 10% fetal bovine serum, and 1 mM mercaptoethanol

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