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Other side effects Additional reported side effects include: Joint pain and water retention Muscle and joint aches Headaches and nausea Receptor desensitization with prolonged use Potential suppression of natural GH and IGF-1 production Who should avoid IGF-1 LR3 Certain groups should not use IGF-1 LR3: Anyone with active cancer or tumor history Those with severe insulin resistance or diabetes Pregnant or nursing women Anyone under 25 whose growth plates haven't closed Those with existing hormonal imbalances IGF-1 LR3 is not FDA-approved for general medical use and remains primarily a research compound

4l, GPX4, PCBP1, and PCBP2 protein levels were reduced in tumor tissues in a dose-dependent manner, which was consistent with the results of the in vitro experiments

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Ding Y, Shen SZ, Sun H, Sun K, Liu F (2014) Synthesis of L-glutathione-capped-ZnSe quantum dots for the sensitive and selective determination of copper ion in aqueous solutions