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[16] Compared to people of the same age without COPD, people with COPD have higher rates of cardiovascular disease, respiratory conditions (lung cancer, pneumonia and asthma), musculoskeletal conditions (osteoporosis), neuropsychiatric conditions (depression, dementia, [13] anxiety [41] [2] [1] ), and metabolic disorders (diabetes mellitus, [41] metabolic syndrome, chronic kidney disease, [42] and skeletal muscle dysfunction)

She later called it the most difficult film I ever did, citing the directors relentless expectations

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