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Low energy Fatigue Memory issues Confusion Headaches Fogginess Moodiness Weakness Anemia Using these symptoms as a guide, you can determine when your vitamin B12 shot needs to be repeated

When you swallow a B12 pill, several steps have to work for it to be absorbed: stomach acid and the enzyme pepsin must release B12 from food or the supplement, the stomach must secrete a protein called intrinsic factor that binds to B12, and the B12-intrinsic factor complex must reach the ileum (the end of the small intestine) where it is finally absorbed

Vitamin B12 injections are generally safe and well-tolerated

Structural healing of tissues (tendons, ligaments) takes longer, with significant improvements visible on imaging at 4-6 weeks