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SKU: 6855788204

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[80] reported that 4-HNE could upregulate cyclooxygenase-2 (COX-2) via activating ATF/CRE and inhibit inducible nitric oxide synthase (iNOS) via inactivating NF-B in OA chondrocytes

Lewis (18751946), and Michael Kasha (19202013) to emphasize the contribution of other researchers to the development of this concept

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