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STORAGE Store tablet and Injection at or below 30 0 C, protect from light and moisture, keep out of reach of children

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In the Methods, we explain why we take the multiplier, S , of the V max values of GCL and GPX to have the following dependence on estradiol, E 2: Thus, since male E 2 is 0.09 nM [26] , S = 1 for the male

Participants Participants were recruited from April 2017 to September 2019 from the Greater Kansas City area via printed flyers, research opportunity advertisements to the community, social media advertisements, and targeted registry mailings (Figure 1)