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123 Multi agonists In recent years, the development of dual and triple agonists related to GLP-1 has been vigorously pursued

These differences in how each peptide may interact with pituitary cells have led some researchers to hypothesize that using both compounds simultaneously may yield synergistic actions on growth hormone secretion, surpassing what either might achieve alone

These microbiotas are capable of producing SCFAs (particularly propionate and butyrate) in the gut, which mitigate the inflammatory response in atherosclerosis by enhancing gut barrier function and inhibiting inflammatory signaling pathways (Huang et al., 2022)