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The anionic nature of superoxide and the fact that it is mostly produced in the mitochondrial matrix determine that the bulk of antioxidant defenses to neutralize superoxide and other ROS reside in the matrix

The structure of the flavoenzyme glutathione reductase

Urinary riboflavin excretion levels in casual or 24h urine specimens reflect dietary intake but vary widely because concentrations are affected by many non-nutritional factors

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