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This work was supported by the Department of Defense Peer Reviewed Medical Research Program grant PR141776 (S.J.W.), University of Texas Medical Branch Technology Commercialization Award (S.J.W), and NIH grant R01GM112936 (C.C.F)

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NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

After he died in 1984, other physicians and naturopaths took up prescribing "intravenous micronutrient therapy" with unsubstantiated health claims for treating fatigue, low energy, stress, anxiety, migraine, depression, immunocompromised, promoting weight loss, and more