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However, advances in the field have brought research to focus on additional biologically important roles ascribed to this versatile enzyme family including cell signaling and post-translational modifications, as well as conferring resistance to chemotherapy, since many GST isoforms have been shown to be overexpressed in numerous cancers

Cancer 122 , 8293 (2020)

Each mL of sterile aqueous solution contains: Cyanocobalamin (B12)..........1000 mcg With sodium chloride 0.22% w/v, ammonium sulfate 0.1% w/v, citric acid 0.01% w/v, sodium citrate 0.008% w/v, and benzyl alcohol 1.0% v/v (preservative)

These advances will rely heavily on the integration of organ-on-chip platforms and digital twin models, enabling continuous in vitro and in silico validation of therapeutic decisions before patient application