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Performing exploratory tests in vitro to predict toxicity in animals minimizes unnecessary in vivo testing and safeguards animal use

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The results summarized in Table 1 further demonstrate that several of the adrenergic compounds, especially epinephrine, norepinephrine and amphetamine, have high affinity for extracellular opioid receptor peptides, with binding constants in the 15 M range, but do not bind significantly to a transmembrane region (OPR 121131)

Simultaneous monitoring of cell number and metabolic activity of specific bacterial populations with a dual gfp-luxAB marker system