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Patients adhered to a standardized wound care protocol, including sharp debridement, daily drug application, pressure-relieving footwear, and diabetes management education

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Many report improved energy, reduced fatigue, better exercise capacity, and reduced carbohydrate cravings

Int J Biochem Cell Biol 38:610620 Williams JL, Holman DW, Klein RS (2014) Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers