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Al Rajabi A 1 , Castro GS, da Silva RP, Nelson RC, Thiesen A, Vannucchi H, Vine DF, Proctor SD, Field CJ, Curtis JM, Jacobs RL

This article will focus on the type of patients or medical conditions that may require the supplementation of vitamin B12 (see the table below).1-6 More importantly, it is necessary to recognize the reason that some of these patients require supplementation, including those using vitamin B12 in different dosage forms other than those to be taken by mouth

Check for drug interactions - Some prescription medicines, like metformin, can deplete B12 over time

In fact, 5060% of Phase 3 drug trials fail, even after strong laboratory and early clinical results