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China doubled its peptide exports to the US in 2025, with shipments approaching half a billion dollars, much of it reaching consumers through platforms like Temu with no guidance on purity or what the product actually contains

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Semaglutide has been actively studied for its ability to reduce hepatic steatosis , improve liver enzyme profiles , and attenuate inflammatory and fibrotic pathways in liver disease models

Renal tubular toxicity was observed in studies up to 14 days in duration in mice and rats at exposures that were generally associated with morbidity and mortality