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The most effective research models evaluate them together to achieve a synergistic "1+1=3" effect on IGF-1 levels

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In particular, metabolic disorders including diabetes, obesity, and hyperlipidemia commonly associated to hypercaloric diets are suspected to affect a woman's fertility either by direct damage to oocyte health and differentiation, or by indirect interference with the pituitary-hypothalamic axis, resulting in dysfunctional oogenesis

The highest pLDDT value of 70 is found in D909 (on a scale of 0100), which corresponds to a ~0.7 probability of correct angles