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Thus, it doesnt seem likely that hypersensitivity to odors is the problem.[ref] Instead, much of the research points to hyper-reactivity to certain compounds, possibly due to altered detoxification pathways.[ref] Oxidative Stress in Multiple Chemical Sensitivity: Scientists have approached MCS from many angles, using genetic, metabolic, immunologic, etiologic, symptomatic, therapeutic, and epidemiologic tools

Diabetes is associated with higher trimethylamine N-oxide plasma levels

It is unknown how these drugs affect endothelial function in MetS patients ( Estradiol increases NO generation and endothelial function