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J Ocul Pharm Ther 2023;39:66171

In fact, cardiovascular outcome trials demonstrated that subcutaneous semaglutide reduces major adverse cardiovascular events in high-risk populations, establishing cardiovascular safety and potential benefit

Sanders SJ, Murtha MT, Gupta AR, Murdoch JD, Raubeson MJ, Willsey AJ, et al

After a 2 week screening period all eligible participants were randomly assigned to treatment groups receiving either a subcutaneous injection of 2.4 mg of semaglutide, 2.4 mg of cagrilintide, a combination of cagrilintide and semaglutide, a semaglutide placebo, or a cagrilintide placebo [2]