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This study follows a previously published pilot study, which found that 500 mg of L-carnitine in combination with 83 mcg selenium (as selenomethionine) taken daily for one month could improve quality of life and symptoms associated with subclinical hyperthyroidism, defined as positive antibodies and a TSH between 0.1-0.4 mIU/L, without modifying thyroid hormone or antibody levels

When all participants were analyzed regardless of treatment adherence, weight reduction trends were consistent with those from the primary analysis, confirming robustness of the findings