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Sun damage does not allow healthy cell formation 3

Cell 179 , 11441159.e1115 (2019)

Nevertheless, if its senolytic action has been demonstrated in several diseases such as osteoarthritis 15,16 as well as in neurodegenerative diseases 17 , the effect of ABT-263 is restricted to senescent cells from specific cell types 18 , leading to the necessity to identify new potential senolytics to target senescent cells in age-related diseases

Differential expression analysis Differential expression analysis was performed with DESeq2 using the Wald test with the fraction of ribosomal RNA included as a covariate