Furthermore, we provide first data that the GSH level in human neurons may be mediated by NMDAR activation since the protective effect of enhanced network activity could be blocked with an NMDAR antagonist APV, consistent with the previous report (Fig
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In addition to GSH effects with T cells, a decrease in GSH plays similar roles in MS as it does in AD and PD, namely, to mark an increase in oxidative stress and inflammation in the respective disease ( Overall, a decrease in GSH is seen across AD, PD, and MS
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