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FIGURE 4 Overexpression of RcGPX4 Enhanced Cold Tolerance at Seed Germination but Reduced Freezing Tolerance at Seedlings Our previous study showed that the protein abundance of RcGPX4 was increased in cold-stressed imbibed seeds (Wang et al., 2019)

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The peptide inhibited hyperglycemia-induced epithelial-mesenchymal transition (EMT) and downregulated fibrosis-related genes, preventing the subretinal fibrosis that represents end-stage proliferative diabetic retinopathy