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Although it produces fewer toxic chemicals than traditional cigarettes, it still contains harmful substances such as nicotine and many other chemicals found in the tobacco plant that can cause cancer and other health problems

Cost Optimization Economies of scale and production improvements are steadily reducing PLA filter costs, making them increasingly competitive with traditional options

Strong recommendation, high certainty Recommendation 11 For people who have abstained from smoking after a standard course of varenicline in combination with behavioural support, clinicians may consider a further course of varenicline to reduce relapse

Participants also showed reductions in self-reported cigarette dependence (-45%), smoking frequency (-29%), and smoking intensity (-78%