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7,11,12 G6PD deficiency is one of a group of congenital hemolytic anemias, and its diagnosis should be considered in children with a family history of jaundice, anemia, splenomegaly, or cholelithiasis, especially in those of Mediterranean or African ancestry

Moreover, exogenous antioxidants obtained in the diet cooperate with endogenous antioxidants to form a supportive network of cellular protection against radical-mediated oxidative stress

TB-500 is under FDA advisory review in July 2026, and FDA staff documents recommend caution because human safety and effectiveness data are limited

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