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In order to translate observed breathing patterns and smoking behavior into biological effects, we combined the small airway-on-a-chip with a smoking machine that burns cigarettes and a microrespirator that inhales and exhales small volumes of cigarette smoke and fresh air in and out of the epithelium-lined channel in programmable intervals mimicking true smoking behavior, said Richard Novak, a co-author of the study and a senior staff engineer at the Wyss Institute, who helped design the smoking instrument

These benefits can be especially helpful for people trying to break a long-term habit without quitting nicotine cold turkey

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You should talk to your own qualified, professional advisors about what is right for your unique circumstances, goals, objectives, and risk tolerance