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It has been suggested that food addiction, similar to drug addiction, may also decrease DD2R

Do supplements with leucine (a branched-chain amino acid or BCAA) prevent muscle loss when muscles are immobilized (such as in a leg brace)

Adequate fiber feeds beneficial bacteria that produce short-chain fatty acids, natural anti-inflammatory compounds that support gut barrier integrity

All SAEs of death, development of signs of critical illness and severe illness requiring hospitalisation, and AEs as described previously will be reported to the Ethics Committees, the Data and Safety Monitoring Board (DSMB) and to the sponsors of the study within 24 hours of awareness of the event, followed by a final report within 10 days