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We think it must be doing this by pumping the carcinogenic compounds from cigarette smoke out of the cells allowing them to survive in the toxic environment. Cell surface pumps, including ABCG2, have also been implicated in the development of multidrug resistance in cancers, presumably by pumping the damaging chemotherapy drugs out of cancer cells

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The vendors also could not display tobacco advertisements that were bigger than 60 by 45 centimeters (24 by 18 inches)