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Description

Experimental neurology 248 , 1629, (2013)

N-Acetylcysteine (NAC): NAC is a powerful precursor to glutathione, supplying the body with the amino acid cysteine, which is crucial for glutathione synthesis

The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor

It has been demonstrated that the amyloid precursor protein-derived C-terminal fragment (APP-CTF) may act as a trigger for AD pathology, with its overaccumulation resulting in impaired mitochondrial structure and defective mitophagy