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And for a lot of people, the issue is with their ability to absorb Vitamin B12 in the gastrointestinal tract - a problem that is also often accompanied by IBS-type symptoms

It does this by inhibiting an enzyme called tyrosinase , which is the key "on switch" for dark pigment production

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That editorial included a caveat that vitamin D supplementation remained an open area of investigation, particularly in deficient persons but nevertheless concluded that current widespread use [of vitamin D supplements] is not based on solid evidence that benefits outweigh harms. Also last year, a study from Massachusetts General Hospital found that many of the 70 percent to 90 percent of African-Americans diagnosed as vitamin D deficient may actually have healthy levels of the vitamin and are not deficient because they are genetically disposed to carry more of the free form of the nutrient