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Interestingly, under specific laboratory conditionstypically involving transgenic animals expressing the species-matched target proteinpathology characteristic of the originating disease can be transmitted to recipient hosts or even cultured cells (Jucker and Walker, 2018

These products, particularly when they are injected, can carry significant health risks, including contamination, infection, local tissue damage or potentially life-threatening reactions

This is often the most noticeable during dose increases, and some studies have also reported that heart rate has also increased