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Low B12 levels are increasingly common, especially in people following vegan or vegetarian diets, those with absorption issues, or individuals experiencing tiredness, low mood, or brain fog

Therefore, the problem that the agents successful in pre-clinical experimental autoimmune encephalitis trials, were either less effective in patients, worsened disease or caused unexpected, severe adverse events (60), may be at least partly solved with the more suited cuprizone model that reflects a toxic experimental model (12)

The information presented here is based on preclinical research, primarily animal studies, and should not be construed as medical advice

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