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For instance, if there is discoloration, cloudiness, or visible particles in the solution, the vial should be discarded immediately, even if the expiration date has not yet been reached

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18 Table 4 Time to Improvement of Abnormalities in Vitamin B12 Deficiency After Initiation of Treatment A 2005 Cochrane review involving 108 patients with vitamin B 12 deficiency found that high-dose oral replacement (1 mg to 2 mg per day) was as effective as parenteral administration for correcting anemia and neurologic symptoms

Again, any surplus passes through harmlessly