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For example: People with gastrointestinal disorders (like Crohns disease or celiac disease) might need more B12 because they absorb less

doi: 10.3390/ph17101384 105 CardinaleDIacopoFCipollaCM

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These findings suggest that microbial dysbiosis exacerbates renal dysfunction in HN by increasing uremic toxin levels and promoting metabolic disturbances and inflammatory reactions ( Figure 2 and Figure 4 ) [38]