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Although analgesics such as NSAIDs are widely used for pain control, they cause some adverse reactions such as upper gastrointestinal bleeding [1, 2, 3]

Addressing these gaps will require integrated multi-omics and subcellular-resolution studies to establish a more precise and context-dependent regulatory framework for ferroptosis

The epigenetic regulation of the expression of GPx1 is therefore a function of the methylation of its coding gene [32]