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In contrast, serine-induced mTOR inhibits Tregs suppressive activity (impeding Foxp3 expression), but this can be reversed by serine degradation to glutathione [110], reinforcing that the manner by which cells metabolize some amino acids can influence their function, being a target for therapies

Borsoi FT, Neri-Numa IA, de Oliveira WQ et al (2023) Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: a mini-review