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Mechanism of action [edit] NNN is metabolized by cytochrome P450, which adds a hydroxy group to either the 2' or 5' carbon on the 5-membered ring

tabacum : Nicotiana tabacum NAB: N-nitrosoanabasine NAT: N-nitrosoanatabine NDMA: N-nitrosodimethylamine NKK: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone NMOR: N-nitrosomorpholine NNN: N-nitrosonornicotine NPIP: N-nitrosopiperidine NPYR: N-nitrosopyrrolidine NSAR: N-nitrososarcosine PAH: Polycyclic Aromatic Hydrocarbons ST: Smokeless Tobacco TSNA: Tobacco-Specific Nitrosamines References Aleksandrova HM (1970) Role of nass in the development of pathological changes in the mouth

With DS products new data are presented for nicotine, and for reducing and total sugars

Thirty years later, it had dropped only slightly, to 1.6 births