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Interestingly, nanoparticle (NP)-induced cell death has been described recently as being consistent with the new 5 R principle

In melanoma prevention and treatment, carotenoids from microalgae demonstrate cytotoxic, antiproliferative, and pro-apoptotic effects against melanoma in vitro and in vivo, including the inhibition of melanoma cell growth through caspase activation, modulation of pro-inflammatory signaling, and induction of cell cycle arrest 187

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Liposomes, being structurally similar to the cell membranes in our body, can fuse more readily with these membranes, facilitating the direct delivery of glutathione into the cells