In the brain, nicotine works mostly to release other neurotransmitterslike dopamine (pleasure), norepinephrine (arousal and appetite suppression), glutamate (learning and memory), endogenous opiates, and serotonin (mood modulation)
Thus, in the present study, we investigate the effect of chronic e-cig exposure and CDP-choline treatment on different hormonal levels including adrenalin, and beta-endorphins, alongside an assessment of serum nicotine and its primary metabolite, cotinine
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