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This finding has important safety implications, as elevated IGF-1 levels associated with full GH therapy raise concerns about increased cancer risk, particularly for individuals with pre-existing malignancies or strong family histories

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Meanwhile, reduction in mean systolic blood pressure (SBP) at week 32 was greater with CagriSema (-13 mmHg) compared with cagrilintide (-3 mmHg) and semaglutide (+ 1 mmHg) [10]

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