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Dr Emma Guymer, a rheumatologist at Monash Health, told Rheumatology Republic there had not been any large, randomised placebo-controlled trials looking at B12 supplementation in patients with fibromyalgia with or without B12 deficiency

For individuals receiving B12 injections for severe deficiency, there have been isolated reports of hypokalaemia (low potassium) during initial treatment, as rapid cell production consumes potassium

In research, angiogenic signaling is a group of pathways and lab readouts used to study vascular patterning and related cellular communication in controlled models

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