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Visalli G, Riso R, Facciol A, Mondello P, Caruso C, Picerno I, et al

10.1038/s41556-018-0176-2 Nat

This suggests CR initiates microenvironmental/stroma-mediated control loss, activates independent proliferation, and stimulates progression of stem cell organoid body formationcancer hallmark factors

Nat Cell Biol 12(2):119131 Gerhardt E, Grber S, Szego EM, Moisoi N, Martins LM, Outeiro TF, Kermer P (2011) Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice