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[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses

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Therefore, neuronal subsets (iSPNs) from mouse striatal tissues of mutants and controls (here called iSPN + mut and iSPN + wt populations, respectively) were genetically labelled in vivo with a fluorescent marker using Rosa26-Ai9-tdTomato strain 21 and purified by fluorescence-activated cell sorting