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It is very effective in helping us discover new candidate drugs, especially in the early stages of drug discovery

doi: 10.3389/fncel.2020.581950 Received 14 July 2020 Accepted 21 December 2020 Published 18 February 2021 Volume 14 - 2020 Edited by Danilo Bilches Medinas, University of Chile, Chile Reviewed by Jorge Matias-Guiu, Complutense University of Madrid, Spain

The 2002 Women's Health Initiative (WHI) study caused widespread fear about HRT, but subsequent reanalysis and decades of follow-up research have clarified the picture significantly