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The mechanism involves an increase in GLUT4 transporter expression, improving glucose uptake

Modulating ion channel activity provides a powerful means of influencing neuronal behavior, offering potential therapeutic avenues for a wide range of neurological and psychiatric disorders ( Ca 2 + ions serve as vital second messengers, regulating key cellular processes such as neurotransmitter release and gene expression (Mitra et al., 2024)

The role appears to be partially mediated through the recruitment of fibroblasts

Type I IFN signaling has also been shown to be significantly elevated in T1D ductal cells when compared to control and AAb+ ductal cells ( HLA-A , HLA-B , and HLA-C (42, 118)