Figure 2 3.1 The metabolism of short chain fatty acids SCFAs, such as acetate (C2), propionate (C3), and butyrate (C4), are produced through the fermentation of dietary fibers and indigestible carbohydrates (such as resistant starch) by the gut microbiome ( Eubacterium , Ruminococcus , Faecalibacterium , and Clostridium clusters IV and XIVa dominate the production of butyrate, while acetate and propionate are associated with Bacteroidetes and Firmicutes ( Studies have found that, compared to healthy relatives, the levels of butyrate in fecal samples from BD patients were significantly reduced and positively correlated with Roseburia ( 3.2 The metabolism of bile acids Cholesterol is metabolized into two primary bile acids in the liver: cholic acid (CA) and chenodeoxycholic acid (CDCA) ( Clostridium , Bacteroides , Bifidobacterium , and Lactobacillus ) and 7-dehydroxylase (mainly expressed by Eubacterium and Clostridium ), respectively ( The expression of TGR5 in M1 macrophages of patients with active VKH is significantly lower than that of healthy controls ( Clostridium scindens in the feces ( C
doi: 10.1016/j.freeradbiomed.2018.09.043 3 JiangXStockwellBRConradM
Four Corners investigates the race to slow, or even reverse, the aging process
The ICR which is both a research institute and a charity is helping more people survive melanoma skin cancer
