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Common symptoms of Biotin Deficiency are as follows: Hair loss (alopecia) Weak/Brittle Nails Dermatitis Skin inflammation is a common symptom of Biotin Deficiency Paresthesia a condition that causes a prickling/tingling sensation in the skin, which is then followed by numbness Hyperesthesia a condition that involves abnormal sensitivity stimuli of the senses Keratoconjunctivitis Sicca Biotin deficiency may also cause an eye disease from eye dryness, which can result in conjunctiva of the eyes Anorexia The condition causes an individual to suffer from poor appetite Anemia The condition causes oxygen-carrying cells (hemoglobin) to lose their ability to bind oxygen