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Brightening the skin can be seen as a side effect of the treatments larger purpose to help address issues that the patient is currently struggling with

Diet, microbiome and symptom context: Diet and microbiome factors can be relevant in selected patients, but they should be considered alongside clinical assessment rather than used as a replacement for evidence based IBD care

The novelty of this review lies in its integrative approach, moving beyond a mere description of disparate pathways to synthesize a coherent framework that connects key metabolic nodessuch as the mammalian target of rapamycin (mTOR)-hypoxia-inducible factor 1-alpha (HIF-1)-glycolysis axis, AMP-activated protein kinase (AMPK)-FAO signalinginto a dynamic immunometabolic network ( Figure 1 )

At the end of the trial, the kids who consumed NAC had a reduction in irritability scores by 80% with minimal side effects