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ATXN3 colocalizes with aggresomes and preaggresome particles of the misfolded cystic fibrosis transmembrane regulator (CFTR) mutant CFTRF508 and interacts with proteins involved in their formation and regulation, such as dynein and histone deacetylase 6 (HDAC6)

Growth factors such as transforming growth factor-beta (TGF-) and insulin-like growth factor-1 (IGF-1) play crucial roles in promoting collagen synthesis and regulating cellular responses to mechanical stress

Neurological Protection Glutathione is the most abundant antioxidant in the brain and plays a central role in protecting neurons from oxidative damage

This method is effective for identifying peptides that selectively bind to targets like enzymes and cellsurface receptors (Song et al., 2024)