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Too much vasoconstriction can lead to increased risk of: Coronary artery disease High blood pressures Hypertension Headaches Heart attack Stroke Finally, nicotine, and specifically nicotine pouches, can also lead to anxiety, irritability, insomnia and mouth sores from the pouches breaking down mucus membranes in your mouth

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1.5 oz tin

The Yale Translational Center for Gender-Sensitive Treatment for Tobacco Dependence conducts basic and clinical research aimed at developing therapies for female smokers, who have lower smoking cessation rates and greater health risks than their male counterparts