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Consequently, loss of FMRP results in an aberrantly increased mGluRI expression in these neurons, leading to enhanced mGluR-related long-term depression causing cognitive impairments and intellectual disability

They estimated that taking Centrum Silver daily for 3 years may slow the rate of cognitive aging by about 60%, which is roughly 1.8 years of protection over 3 years

Mutation of a nicotinic acetylcholine receptor subunit is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae

ROS and reactive nitrosylation species (RNS) also act as critical signaling molecules that modulate synaptic strength, neurotransmitter release, and cerebral blood flow [367]